Calocurb is a weight management supplement that has been developed over a period of more than 13 years at the New Zealand Institute for Plant and Food Research.

Its efficacy is attributed to its active ingredient, Amarasate® , which is an extract from a specific variety of NZ hop flower - identified as having the ability to activate and enhance the body’s natural feeling of fullness or satiety. 

Amarasate ® is released into the small intestine, specifically the duodenum, from a delayed release patented capsule.

After only one hour, it stimulates the TAS2R receptors on enteroendocrine cells to release gastric hormones (GLP-1 and CCK) at 6 times baseline levels, twice the normal post-prandial release. 

Clinically shown to;

• Reduce caloric intake by an average of 18%
• Reduce changes in hunger by up to 100%
• Reduce changes in cravings by up to 120%

Mode of Action

Calocurb's journey began with the discovery of Amarasate® in 2013, a groundbreaking, potent extract that has been demonstrated to stimulate the enhanced release of satiety hormones.

Amarasate® is a natural extract of New Zealand bitter hops that has been demonstrated in clinical trials to regulate and reduce appetite, craving, and caloric intake. Amarasate ® is released into the small intestine, specifically the duodenum, from a delayed release patented capsule (Walker et al., 2022)

• After only one hour, it stimulates the TAS2R receptors on enteroendocrine cells to release gastric hormones (GLP-1 and CCK) at six times baseline levels, twice the normal post-prandial release (Walker et al., 2022). 
• These gastric hormones signal a part of the brain to decrease appetite and food cravings plus slow down the gastric emptying rate.